Mediation of arachidonic acid metabolite(s) produced by endothelial cytochrome P-450 3A4 in monkey arterial relaxation.
Cytochrome P450-dependent arachidonic acid metabolites, 19- and 20-hydroxyeicosatetraenoic acids, enhance sodium-potassium ATPase activity in vascular smooth muscle.
Cytochrome P450 pathways of arachidonic acid metabolism.
Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation.
Abnormal pressure-natriuresis in hypertension: role of cytochrome P450 metabolites of arachidonic acid.
P-450 metabolites of arachidonic acid in the control of cardiovascular function.
2] were the major metabolites of arachidonic acid studied among the three Allium species.
Since, as far as is known, indomethacin is not an inhibitor of lipoxygenase, it is highly possible that cyclo-oxygenase was involved in the above-mentioned conversion of arachidonic acid to prostaglandins and a thromboxane.
2] in corn leaf homogenates that were incubated with 3H-labeled arachidonic acid.
The compounds are arachidonic acid derivatives, and inherent in these seaweed natural-product structures is evidence of a highly evolved lipoxygenase-type metabolism that matches or exceeds the complexity of comparable metabolic routes in mammalian systems.
Labeled arachidonic acid applied to an extract of the alga produced a pheromone, dictyotene.
By imposing nitrogen starvation, it was possible to obtain a lipid mixture that may be separated in arachidonic acid and eicosapentaenoic acid-rich fractions.