Arctium


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Related to Arctium: Arctium lappa

Arctium

 

a genus of plants of the family Compositae. Members are biennial large grasses with large leaves. The blossoms are monoecious, tubular, and usually purple, in round calathides that are gathered into a common raceme. When the fruits ripen the calathides readily break off, sticking to the coats of animals and the clothing of man. The achenes are compact and have a crest of numerous rows of fibers.

There are about ten species in temperate areas of Europe and Asia; the USSR has six to eight species that grow primarily in inhabited areas, trash heaps, deserted areas, along roads, and in vegetable gardens; they sometimes infest cultivated fields. The most common are cotton burdock (A. tomentosum) and common burdock (A. lappa, A. majus). A decoction from the roots, which contain inuline, organic acids, essential oils, and other substances, is used as a diuretic and diaphoretic; a tincture of the roots with almond or olive oil is used as a hair tonic. Decoctions and pastes from the roots are also used in treating rheumatism, gout, and skin diseases. Young roots and shoots are edible. The plants are rich in nectar.

REFERENCE

Atlas lekarstvennykh rastenii SSSR. Moscow 1962.

T. V. EGOROVA

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Extraction and isolation of lignans from Arctium lappa
lappa extract were performed as described in our article: natural lignans from Arctium lappa as novel antiaging agents in Caenorhabditis elegans (submitted to Phytochemistry).
In the present study, we found that the major lignans isolated from Arctium lappa seeds possess promising MDR reversal activities in CEM/ADR 5000 and CaCo2 cell lines, which overexpress P-gp and other ABC transporters.
Lappaol F, a novel anticancer agent isolated from plant Arctium lappa L.
In this study a fraction containing the lactone sesquiterpene onopordopicrin (ONP) from Arctium lappa was administered orally as either 25mg/kg daily or 50mg/kg daily 48, 24 and 1 hour before the induction of colitis in rats by the administration of 2,4,6 trinitrobenzene sulfonic acid (TNBS).
These results, while preliminary and only reflecting a small animal study, suggest a potential therapeutic use for Arctium lappa in inflammatory bowel disease such as Crohn's disease and ulcerative colitis.
Anti-proliferative and a poptotic effects of butyrolactone lignans from Arctium lappa on leukemic cells.
Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa U.
Two polyacetylenic phytoalexins from Arctium lappa.
Keywords: Arctiin; Arctium lappa: Glomerulonephritis; Nuclear factor-KB; Pro-inflammatory cytokine; Superoxide dismutase
Fructus Arctii, the dried fruits of Arctium lappa L.
Arctiin was isolated and purified from the fruits of Arctium lappa L.