Inhibitor

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Related to Aromatase inhibitors: tamoxifen

inhibitor

[in′hib·əd·ər]
(aerospace engineering)
A substance bonded, taped, or dip-dried onto a solid propellant to restrict the burning surface and to give direction to the burning process.
(chemistry)
A substance which is capable of stopping or retarding a chemical reaction; to be technically useful, it must be effective in low concentration.

Inhibitor

 

a circuit having m + n inputs and a single output, at which a signal can appear only when there are no signals on the m inputs (inhibiting). The other n inputs (principal) form one of the two logic connections, “AND” or “OR.” Inhibitors are used extensively in computers. They are very often understood to be a circuit having a single principal input and a single inhibiting input. A signal appears at the output of such a circuit when a signal is present on the principal input but there is none on the inhibiting input. Such an inhibitor is called an anticoincidence gate; its conventional representation is given in Figure 1.

Figure 1. Block diagram of an anticoincidence gate (inhibitor) with m — 1 and n 1:(A) principal input, (Q) inhibiting input, (Ga) anticoincidence gate

inhibitor

A substance added to paint to retard drying, skinning, mildew growth, etc. Also see corrosion inhibitor, inhibiting pigment, drying inhibitor.
References in periodicals archive ?
It found that aromatase inhibitors saved more lives than tamoxifen.
Food and Drug Administration (FDA) has designated entinostat as a Breakthrough Therapy for the treatment of locally recurrent or metastatic estrogen receptor-positive (ER+) breast cancer when added to exemestane in postmenopausal women whose disease has progressed following non-steroidal aromatase inhibitor therapy.
And there can be real benefits of taking aromatase inhibitors.
Arimidex: a potent and selective fourth-generation aromatase inhibitor.
The findings suggest that vitamin D supplementation at doses higher than the standard of 400-800 IU/day might be useful to minimize bone loss in women starting out on aromatase inhibitors and who are not eligible for bisphosphonate therapy according to current guidelines.
A phase 3 study of the effect of denosumab therapy on bone mineral density in women receiving aromatase inhibitors for non metastatic breast cancer.
Stephanie Boyle, a mother-of-two from Derwent Road, Cullercoats, North Tyneside, has been getting treatment with aromatase inhibitors for the last two months.
This is the first head-to-head study of these two aromatase inhibitors in the post-surgery setting and is expected to enrol 4,000 women worldwide.
The National Institute for Health and Clinical Excellence (Nice) has recommended the use of aromatase inhibitors, which include drugs such as femara for treating early breast cancer in postmenopausal women immediately after surgery.
Educating readers on the whole process of discovering breast cancer and guiding readers through an informed approach to the diagnosed condition possible, Dancing With Fear tactfully presents an easy-to-follow guideline of finding the tumor, dealing with the doctors and surgeries, lymphedema, chemotherapy and radiation, tamoxifen and aromatase inhibitors, fear of recurrence, complementary and alternative treatments, optimism and pessimism, support and humor, spirituality and facing death, and aftermath and reclaiming life.
Liz Caroll, from charity Breast Cancer Care, said: "These results further suggest the benefits of using aromatase inhibitors over tamoxifen in treating early invasive breast cancer and indicate that many more lives could be saved.
Today a new class of anti-estrogen drugs called aromatase inhibitors seems to work even better.