Arthrogryposis(redirected from Arthrogryposis renal dysfunction cholestasis syndrome)
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a congenital disease manifested in flexure (contracture) of the joints of the extremities as a result of atrophy of the muscles and replacement of muscle fibers by fatty tissue. In arthrogryposis the upper extremities are pressed to the torso and the elbow joints are unbent; the wrists and fingers are bent and adducted, resembling the talons of a predatory bird. The lower extremities are bent and abducted at the hip joints and unbent at the knees. The feet are deformed (clubfoot). The treatment is orthopedic—corrective splints, operations, and exercises. The earlier the treatment, the better the results.