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artificial chromosome |
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artificial chromosome [‚ärd·ə¦fish·əl ′krō·mə‚sōm] (genetics) A functional chromosome constructed by genetic engineering, having a centromere (and a telomere at each end, if linear rather than circular) and thus transmissable in cell division after introduction into a cell. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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NIAS and STAFF will produce a draft sequence of the genome from the Bacterial Artificial Chromosome region commissioned by the Sanger Institute. In 2002 Kirin made use of a proprietary human artificial chromosome vector to introduce human antibody genes into bovine cells and, using Hematech's technology, created cows capable of producing human antibody proteins and bovine antibody proteins. Chromosome loss is very common in chromosome preparation, so there were only 71% diploids in normal diploid group in this study, others being represented as aneuploids after artificial chromosome loss. |
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