Trypsinogen

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trypsinogen

[trip′sin·ə·jən]
(biochemistry)
The zymogen of trypsin, secreted in the pancreatic juice. Also known as protrypsin.

Trypsinogen

 

an inactive precursor (proenzyme) of the proteolytic enzyme trypsin. Trypsinogen is synthesized in the pancreas and converted into trypsin—the active enzyme—in the small intestine. The activation of trypsinogen entails the cleavage of a short peptide fragment from the N-terminal of the trypsinogen molecule by the enzyme enterokinase or by trypsin itself.