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asymmetric synthesis
(redirected from Asymmetric catalysis)

   Also found in: Wikipedia 0.01 sec.

asymmetric synthesis

Chemical reaction by which unequal amounts of two product isomers are formed. It is normally not possible to synthesize from materials that do not have optical activity (i.e., are not chiral) one stereoisomer of a chiral compound without the other, but use of a chiral auxiliary, such as an enzyme or other catalyst, a solvent, or an intermediate, can force the reaction to produce predominantly or only one isomer. Asymmetric syntheses are often called stereoselective; if one product forms exclusively, it is stereospecific.


asymmetric synthesis [¦ā·sə¦me·trik ′sin·thə·səs]
(organic chemistry)
Chemical synthesis of a pure enantiomer, or of an enantiomorphic mixture in which one enantiomer predominates, without the use of resolution.


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Sepracor plans to use this process, called asymmetric catalysis, to produce starting compounds for pharmaceutical manufacturers.
Asymmetric catalysis is an important aspect of asymmetric synthesis, and one that has seen tremendous activity over the past decade.
of Pennsylvania) have written this comprehensive textbook on asymmetric catalysis to underline the importance of stereochemistry to students and practitioners of pharmacology, biology, agricultural sciences and materials science.
 
 
 
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