asymmetric synthesis

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asymmetric synthesis

[¦ā·sə¦me·trik ′sin·thə·səs]
(organic chemistry)
Chemical synthesis of a pure enantiomer, or of an enantiomorphic mixture in which one enantiomer predominates, without the use of resolution.
References in periodicals archive ?
The applicant~s previous research experience in C-H activation, ionic liquids catalysis and asymmetric catalysis areas will benefit the project.
Chemists explain the theory, practice, and results of combining multiple distinct catalysts--at least one of them chiral--as a promising strategy to tackle challenges in achieving ideal asymmetric catalysis.
Summary: Development in the field of asymmetric catalysis is driven by the importance of stereochemically pure compounds in the field of pharmaceutical industry, agrochemicals and flavors.
Cramer heads the laboratory of asymmetric catalysis and synthesis at the Ecole Polytechnique Federale (EPF) in Lausanne, Switzerland.
Among the topics are enantioselective annulations with chiral N-mesityl N-heterocyclic carbenes, the construction of anti-Me-OH vicinal relationships in polyketides, asymmetric catalysis in the total synthesis of lipids and polyketides, hetercycle construction via asymmetric rhodium-catalyzed cylcoadditions, and dynamic kinetic asymmetric transformations involving carbon-carbon bond cleavage.
Asymmetric catalysis using nanoparticle-based catalysts is quite rare, and could have its advantages.
Despite the fact that our resources were limited at the time, we were able to find spare parts and assemble a number of chromatography instruments to further our research on asymmetric catalysis.
In this work, they present 13 review articles describing various aspects of this emerging field, including asymmetric synthesis of chiral sulfoxides, asymmetric synthesis of optically active sulfinic acid esters, asymmetric transformations mediated by sulfinyl groups, synthesis and applications of chiral dithiocetal derivatives, synthesis and use of chiral sulfur ylides, synthesis and use of chiral sulfoximines, synthesis and use of chiral sulfinamides, asymmetric catalysis using sulfoxides as ligands, sulfones in asymmetric catalysis, and computational studies on asymmetric reactions with sulfur reagents.
Sepracor plans to use this process, called asymmetric catalysis, to produce starting compounds for pharmaceutical manufacturers.
The study of stereoselectivity has evolved from issues of diastereoselectivity, through auxiliary-based methods for the synthesis of enantiomerically pure compounds (diastereoselectivity followed by separation and auxiliary cleavage), to asymmetric catalysis.
The topics include homogeneous gold-catalyzed oxidation and reduction reactions, the gold-catalyzed addition of a heteroatom nucleophile to a carbon-carbon multiple bond, gold-catalyzed multi-component reactions, gold catalysis on tandem and cascade reactions, gold-catalyzed reactions of propargylic esters, recent developments in asymmetric catalysis, and gold catalysis in natural products synthesis.