Pancreatitis

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pancreatitis

[‚pan·krē·ə′tīd·əs]
(medicine)
Inflammation of the pancreas.

Pancreatitis

 

acute or chronic inflammation of the pancreas.

Acute pancreatitis may be edematous, hemorrhagic, necrotic, or purulent. It is caused by overeating; by diseases of the stomach, duodenum, biliary tract, or liver; or by stenosis of the gland’s ducts. In acute pancreatitis the pancreas is digested by its own enzymes—trypsin, chymotrypsin, and lipase. When the gland’s tissue decomposes, kinins are released. They decrease arterial pressure and are a factor in blood circulation disorder of both organic and reflex origin in the pancreas. The kinins also cause bile to flow into the gland’s ducts, which damages their walls.

Acute pancreatitis may be marked by very severe abdominal pains, persistent vomiting, and collapse. Complications are peritonitis, abscesses, cysts of the gland, and diabetes mellitus. The disease is treated by narcotics, antibiotics, vasoconstrictors, and such antienzyme preparations as trasilol and contrical and by A. V. Vishnevskii’s paranephric novocain blockade. Serious complications are treated surgically.

In chronic pancreatitis, the gland’s external and internal secretions gradually become insufficient. The disease is treated by diet, antispasmodics, substitutes, cholegogues, antibiotics, and antienzyme preparations. During periods of remission, the patient may receive treatment at a health resort.

REFERENCE

Shelagurov, A. A. Bolezni podzheludochnoi zhelezy. Moscow, 1970.

O. S. RADBIL’

References in periodicals archive ?
At least in Japanese populations, IgG4-related autoimmune pancreatitis has a male to female ratio of 3-4:1, (11) but this ratio decreases nearly to unity in the context of head and neck disease.
Autoimmune pancreatitis and complement activation system.
IgG4-associated cholecystitis: another clue in the diagnosis of autoimmune pancreatitis.
Retroperitoneal disorders associated with IgG4-related autoimmune pancreatitis.
Clinical and Immunopathologic Profile of Mexican Patients with IgG4 Autoimmune Pancreatitis.
Hilar and pancreatic gallium-67 accumulation is characteristic feature of autoimmune pancreatitis.
International Consensus Diagnostic Criteria for Autoimmune Pancreatitis Guidelines of the International Association of Pancreatology.
Clinical differences between primary sclerosing cholangitis and sclerosing cholangitis with autoimmune pancreatitis.
Chronic pancreatitis caused by an autoimmune abnormality: proposal of the concept of autoimmune pancreatitis.
If a patient has preexisting autoimmune disease such as Sjogren's syndrome or systemic lupus erythematosus, autoimmune pancreatitis is a likely diagnosis.
87,89,117) As explained earlier, the pathologic features of thyroid involvement are very similar to those of other organs affected in the systemic form of IgG4-RD, (90) especially autoimmune pancreatitis (as more than one-third of affected patients (118) have some form of thyroiditis as well, (90,119) and include diffuse lymphoplasmacytic infiltration, lymphoid follicle formation with germinal centers, dense stromal fibrosis, and follicular cell destruction (Figure 7, A through C).
Autoimmune pancreatitis is characterised by diffuse enlargement of pancreas, narrowing of pancreatic duct, lymphoplasmacytic infiltrations and fibrosis.

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