autophagy

(redirected from Autophagolysosome)
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Related to Autophagolysosome: Autophagocytosis

autophagy

[′ȯd·ə‚fā·jē]
(cell and molecular biology)
The cellular process of self-digestion.
References in periodicals archive ?
In aged RPE cells the substrate for autophagy is degraded by lysosomal acid hydrolases, including cathepsins D, B, and L, after autophagolysosome, and Rab7, LAMP-2A, and SNAREs proteins are critical for the fusion of lysosome and autophagosome.
sup][10] In peri-nucleus of ECs, a high nonhomogeneous density of cellular components was detected and regarded as autophagolysosome.
Mature autophagosomes then fuse with lysosomes to form autophagolysosomes, where the sequestered cargo is subsequently degraded [101].
20],[21] This may be due to the accumulation of lysosomes and autophagolysosomes in neurites or glial cells around amyloid plaques.