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azole |
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azole [′ā‚zōl] (organic chemistry) One of a class of organic compounds with a five-memberedN-heterocycle containing two double bonds; an example is 1,2,4-triazole. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii. Clinical isolates exhibited decreased susceptibility to antifungal drugs, especially azoles. This broad use of azoles is based on their inhibition of certain pathways of steroidogenesis by high-affinity binding to the enzymes sterol 14[alpha]-demethylase and aromatase. |
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