B cell

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Related to B-cells: Plasma B cells

B cell

[′bē ‚sel]
(immunology)
One of a heterogeneous population of bone-marrow-derived lymphocytes which participates in the immune responses. Also known as B lymphocyte.
References in periodicals archive ?
Activated antigen-specific B-cells are viewed as very potent antigen-presenting cells (APC) that can endocytose, process and present antigen at least 10 000-fold more efficiently than other professional APC, (5) largely because B-cells can selectively internalize antigen through the B-cell receptor, and efficiently stimulate T-cells through co-stimulatory molecules such as CD80 and CD86 (which are ligands for CD28 and CTLA-4 expressed on T-lymphocytes).
Ofatumumab is an investigational, fully human, next generation monoclonal antibody that targets a unique epitope of the CD20 receptor on the surface of B-cells.
This allows ZEVALIN to specifically target B-cells, destroying the malignant NHL B-cells and also normal B-cells.
No one knows what role the factors play in the disease, but Edwards contends that they set off a "vicious cycle" of B-cell activity.
Professor Jonathan Edwards, the scientist leading the team, said the new treatment involved drugs that seek out and destroy B-cells.
Antibodies are made by lymphocytes called B-cells '
GA101 targets CD20 proteins found on B-cells, and is designed to result in cell death.
B-cells represent a critical component of human immune response to infection and other pathogens.
Diabetes is a dysfunction understood as a result of either insulin inefficiency (resistance) or decreased insulin secretion from the B-cells of pancreas.
Stem cells (B-cell progenitors) in bone marrow lack the CD20 antigen, allowing healthy B-cells to regenerate after treatment and return to normal levels within several months.
GIFT15 can take your normal, run-of-the-mill B-cells and convert them - in a Superman or Jekyll -Hyde sort of way -into these super-powerful B-regulatory cells," said Galipeau.
B-cells are crucial pathogenic elements in the induction and development of RA.