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B cell |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.07 sec. |
B cellOne of the two types of lymphocytes (the others being T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity; on encountering a foreign substance (antigen), the B lymphocyte differentiates into a plasma cell, which secretes immunoglobulin (see antibody). B cell [′bē ‚sel] (immunology) One of a heterogeneous population of bone-marrow-derived lymphocytes which participates in the immune responses. Also known as B lymphocyte. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Mitogens chosen in the lymphocyte proliferation assay were phytohemagglutinin (PHA) and concanavalin A (ConA) for T-lymphocyte stimulation, and lipopolysaccharide (LPS) and phorbol 12,13-dibutyrate (PDB) for B-lymphocyte stimulation. Sidman uses a strain of transgenic mice that always develop B-lymphocyte tumors. Accordingly, Rituxan promotes the elimination of both cancerous and normal B-lymphocytes bearing this antigen. |
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