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B cell |
Also found in: Medical, Wikipedia, Hutchinson | 0.06 sec. |
B cellOne of the two types of lymphocytes (the others being T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity; on encountering a foreign substance (antigen), the B lymphocyte differentiates into a plasma cell, which secretes immunoglobulin (see antibody). |
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Elaboration of such viral proteins as LMP1, essential to the immortalization of EBV-infected B-lymphocytes, may affect EBV infection of T lymphocytes, although studies suggest otherwise (59). In healthy people, B-lymphocytes divide and secrete antibodies to combat microbial enemies. Accordingly, Rituxan promotes the elimination of both cancerous and normal B-lymphocytes bearing this antigen. |
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