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vaccine
(redirected from BCG vaccine)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.04 sec.

vaccine

Preparation containing either killed or weakened live microorganisms or their toxins, introduced by mouth, by injection, or by nasal spray to stimulate production of antibodies against an infectious agent. This confers immunity to that agent, since the B lymphocytes remain sensitized to it and respond to later infection by producing more antibodies. The first vaccine, against smallpox, was introduced by Edward Jenner in 1798. Vaccines have been developed against diseases caused by bacteria (e.g., typhoid, whooping cough, tuberculosis) and by viruses (e.g., measles, influenza, rabies, poliomyelitis). Effectiveness varies, and a small percentage of people have adverse reactions. Those with immunodeficiency disorders should not receive live vaccines.
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? Mentioned in ? References in periodicals archive
 
Methodological considerations in case-control studies to evaluate BCG vaccine effectiveness.
Risk factors for Buruli ulcer, Benin by Dramaix, Michele / Emerging Infectious Diseases
The scientists gave the new vaccine to 17 volunteers who had received the BCG vaccine in the past--as recently as within a year or as long as 38 years ago.
TB vaccine gets a needed boost by Science News
Although the BCG vaccine offers protection against the most serious forms of TB in childhood, its efficacy wanes over a period of 10-15 years after the vaccination.
AERAS/CRUCELL TO DEVELOP TB VACCINE by Worldwide Biotech
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