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BRCA gene

   Also found in: Medical, Wikipedia, Hutchinson 0.03 sec.
BRCA gene: see breast cancer breast cancer, cancer that originates in the breast. Breast cancer is the second leading cause of cancer death in women (following lung cancer ). Even allowing for improvements in detection (i.e.
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Kretchmer's genetic mutation -- the BRCA gene -- increases the chances of breast and ovarian cancer, the latter which killed her maternal grandmother.
A mutation in either BRCA gene also confers an increased risk of ovarian cancer.
The investigators paired women-who had had invasive breast cancer diagnosed during 1970-2001 (cases) with women who had never received a diagnosis of this cancer (controls); they matched each pair for year of birth, country of residence, BRCA gene mutated and history of ovarian cancer.
 
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