BRCA gene

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Related to BRCA gene: BRCA2 gene, Lynch syndrome

BRCA gene:

see breast cancerbreast cancer,
cancer that originates in the breast. Breast cancer is the second leading cause of cancer death in women (following lung cancer). Although the vast majority of the cases occur in women, some men also get breast cancer.
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References in periodicals archive ?
It is intended for women with heavily pretreated ovarian cancer that is associated with defective BRCA genes.
Audeh said at least seven other PARP inhibitors are in development and testing for cancers associated with BRCA gene mutations, and for others that may stem from similar mutations.
But while competitors now have more flexibility to devise tests that compete with Myriad's, the exclusion for complementary DNA means that Myriad retains much of its patent strength around the two BRCA genes.
Myriad's patent-authorized monopoly on BRCA gene testing may have ended, but its legacy will continue.
Mrs Duncan, who is married to Graeme, 43, a civil engineer, said: "It is great that research is being done into the BRCA gene and it is extremely important that the North East is at the forefront of research.
The argument that Antonia and Julie make in favour of the pregnancy hinges on the fact the BRCA gene could mean a premature hysterectomy for Antonia, depriving her of another chance to have a baby - like her sister, Jasmine.
In our practice, we have noticed that women with a known deleterious BRCA gene mutation are being diagnosed earlier with the disease than their moms or aunts," notes Utton, the study's first author.
Limited family structure and BRCA gene mutation status in single cases of breast cancer Weitzel JN, Lagos VI, Cullinane CA et al.
Gemma Wilkie, a spokeswoman for the HFEA, said: "I can confirm that the HFEA has granted a licence to the University College Hospital in London to use PGD (pre-genetic diagnosis) to screen for the BRCA gene which causes a susceptibility to inherited breast cancer.
Kretchmer's genetic mutation -- the BRCA gene -- increases the chances of breast and ovarian cancer, the latter which killed her maternal grandmother.
The investigators paired women-who had had invasive breast cancer diagnosed during 1970-2001 (cases) with women who had never received a diagnosis of this cancer (controls); they matched each pair for year of birth, country of residence, BRCA gene mutated and history of ovarian cancer.