Hyperpolarization-activated cyclic nucleotide (HCN) channels, which are also stronglylinked to mechanoreception in arterial
baroreceptors, are shown to be upregulated in type 1 diabetes mellitus leading to a reduced
baroreceptor function that can be rescued with tempol [22].
sup][12] In addition, surgical removal of a carotid plaque caused immediate partial disruption of the
baroreceptor activity leading to increased arterial pressure instability.
Arterial
baroreceptor information affects striatal dopamine release measured by voltammetry in rats.
He further explained that if their hypothesis is proven right then arterial stiffness and
baroreceptor signaling will become hotspot targets for the treatment of high blood pressure and the development of new medicines and medical devices.
Moreover, our findings strongly suggest that NADH-stimulated RMSAP might be under the inhibitory control of aortic
baroreceptors, suggesting again that this response could be mediated by an increase in baseline efferent RSNA.
5] However, the limitations of our study include the small sample size; use of a sphygmomanometer to record BP instead of beat-to beat-BP monitoring (which would have helped determine BP variability and
baroreceptor sensitivity) and use of the isometric hand- grip test which is considered insensitive in assessing sympathetic activity.
Influence of smoking on
baroreceptor function: 24 h measurements.
The system works by electrically activating the
baroreceptors located in the carotid artery, the body's natural blood pressure sensors that regulate cardiovascular function.
Baroreceptors could be considered as playing part of a shared physiological modulatory mechanism.
The increased central blood volume via arterial
baroreceptors imposes a greater vagal activation and reduces heart rate and cardiac output (Rowell, 1993).
IX),
baroreceptors (X), pulmonary distension receptors (X), intestinal
Reflex effects of hepatic
baroreceptors on renal and cardiac sympathetic nerve activity.
