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Barr body |
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Barr body [′bär ‚bäd·ē] (cell and molecular biology) A condensed, inactivated X chromosome inside the nuclear membrane in interphase somatic cells of women and most female mammals. Also known as sex chromatin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The underlying premise of these studies has been based on the Lyon hypothesis, which assumes that only one X chromosome is active in any female cell, the other X chromosome remaining in an inactive state as a Barr body, and that the X chromosome that is inactivated (methylated) is determined randomly. In 1959, Japanese cell biologist Susumo Ohno announced that each Barr body was an X chromosome, albeit a highly compacted one. |
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