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bcl-2

   Also found in: Medical, Acronyms, Wikipedia 0.01 sec.
bcl-2
(biochemistry)
A family of proteins that operate in the effector phase of apoptosis and may either promote or inhibit apoptosis.


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Mcl-1 is part of the Bcl-2 protein family, and is regulated by B-RAF proteins, which are mutated in approximately 60 percent of all human melanomas.
The pro-apoptotic gene Bax showed lower transcript and protein levels, whereas the anti-apoptotic gene Bcl-2 showed higher levels in CTPE cells.
Bcl-2 antigen staining was visualized by NovaRED substrate, and other reactions were visualized by DAB substrate (both from Vector).
 
 
 
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