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Bence-Jones protein
(redirected from Bence Jones protein)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.02 sec.
Bence-Jones protein [¦bens ¦jōnz ¦prō‚tēn]
(pathology)
An abnormal group of globulins appearing in the serum and urine, usually in association with multiple myeloma and characterized by coagulation at 50-60°C.


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CT and measurements of serum immunoglobulin and urinary Bence Jones protein levels may be useful in detecting recurrence or conversion to multiple myeloma.
Consequently, very high urinary B2M levels can be a potential source of interference when Bence Jones protein excretion is quantified by urine protein electrophoresis (UPEP) studies.
In addition, the Bence Jones protein may go undetected in the urine when immunofixation electrophoresis is negative and the patient is not symptomatic.
 
 
 
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