Background and Objective: Substituted benzylamines
are important intermediates in the synthesis of numerous biologically active compounds, including agrochemicals and pharmaceuticals.
I think all the agents--the azoles, allylamines, benzylamines
, and ciclopirox--are going to work fairly well if you make a good choice for what you're trying to treat.
The reaction of certain organic acids (for example, 3,5 pyrazoledicarboxylic acid) with amines, such as benzylamines
and alkylamines, has led to hydrogen-bonded pillared clay mimics, and by varying the organic acid and amine used, a variety of predictable layered structures can be synthesized.
The market is dominated by generics classes such as azoles, allylamines and benzylamines
, which offer good safety and tolerability profiles, thereby creating strong competition among these products.
Butenafine is the first of a new class of antifungal agents known as the benzylamines
, which are chemically and pharmacologically related to the allylamine antifungal drugs.
This method can also be used for the synthesis of other hydroxy-substituted benzylamines
These benzylamine bridges (or aminomethylene bridges in the melamine-formaldehyde and melamine-urea-formaldehyde cases) are temperature stable for long periods, even at relatively high temperatures, and dominate resin cross-linking.
This peak is one of the peaks that has been shown to belong to an aromatic carbon to which is attached a benzylamine bridge (Pichelin et al.
An interesting point to note is the absence of unreacted free C6 and C8 sites on the very reactive A-ring, which is a clear indication that these two sites have been totally reacted with benzylamine bridges or they are occupied by the interflavonoid bond.