Compared with gamma radiation--based brachytherapy, beta radiation
involves far less radiation exposure to catheterization laboratory personnel.
NeoVista's epiretinal beta radiation
therapy is currently being studied in a definitive Phase III clinical study to support eventual filing for regulatory approval to market the product in the United States.
All HIV-uninfected patients were treated with adjunctive beta radiation
, and none experienced recurrences during the study period.
Any possible health effects from it are the result of the beta radiation
131]I emits mostly beta radiation
, which penetrates surfaces more shallowly than gamma radiation.
Sirtex's SIR-Spheres microspheres are radioactive polymer spheres that emit beta radiation
In contrast, NeoVista's therapy applies a targeted dose of beta radiation
to the leaking blood vessels that affect central vision; concomitantly, two injections of an anti-VEGF agent are delivered one month apart to maximize the acute therapeutic response and additional anti-VEGF injections are given on a PRN basis.
announced today that the first European patient has been treated in the company's pivotal global clinical trial for its novel beta radiation
epiretinal therapy for the wet form of age-related macular degeneration (AMD).
EndoSonics has been developing the device, named BRIGADE -- Beta Radiation
with IVUS Guidance And Directed Energy -- in conjunction with Drs.
For alpha and beta radiation
, all monitored median values were consistent with median values for a reference air monitor placed away from the site in St.
NeoVista's revolutionary therapy applies a targeted dose of beta radiation
to the leaking blood vessels that affect central vision; concomitantly, two injections of an antiA vascular endothelial growth factor (anti-VEGF) agent are delivered to maximize the acute therapeutic response.
It combines the targeting ability of an anti-CD20 monoclonal antibody with the cytotoxic power of beta radiation
emitted by the yttrium-90 isotope -- a pure beta emitter.