beta-lactamase

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beta-lactamase

[¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.
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References in periodicals archive ?
Novel plasmid mediated beta lactamases in Enterobacteriaceae: emerging problem for new beta-lactam antibiotics.
According to industry sources, several million beta lactamase screening tests are performed each year.
Several noted specialists in the field of microbiology have published reports indicating excellent results with Beta-L RED Discs in detecting the production of beta lactamase by clinical isolates of bacteria.
ESBL phenotypes and prevalent genotype of CTX-M type beta lactamases in clinical isolates of E.
Microbiology studies of NXL 104 in combination with ceftaroline demonstrated that NXL 104 increases ceftaroline's activity against beta lactamase producing gram negative pathogens.
Currently, CLSI documents do not indicate the screening and confirmatory tests that are optimal for detection of these beta lactamases (8).
It has been stated that the amp C beta lactamases when present along with ESBLs can mask the phenotype of the latter (3).
A functional classification scheme for beta lactamase and its correlation with molecular structure.
Plasmid coded metailo beta lactamase (imp 6) conferring resistance to carbapenems, especially meropenam.
Evaluation of extended spectrum beta lactamase in urinary isolates.
Extended spectrum beta lactamase production and multidrug resistance in Klebsiella species isolates from children under five with intestinal & extraintestinal infections.