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beta catenin |
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beta catenin [‚bād·ə ′kat·ən·in] (biochemistry) A multifunctional protein that is involved in Wnt signal transduction and plays an essential role in intercellular adhesion. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Polycyclic aromatic hydrocarbons disrupt axial development in sea urchin embryos through a beta-catenin dependent pathway. In some cases of brain cancer, for example, beta-catenin drives unchecked cell proliferation. In general, these mutations involve Wnt signal transduction proteins including the activation of beta-catenin and inactivation of the (APC) adenomatosis polyposis coil protein. |
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