lactam

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Related to Beta-lactam Ring: beta-lactamase

lactam

[′lak‚tam]
(organic chemistry)
An internal (cyclic) amide formed by heating gamma (γ) and delta (δ) amino acids; thus γ-aminobutyric acid readily forms γ-butyrolactam (pyrrolidone); many lactams have physiological activity.
References in periodicals archive ?
Penicillinase is a specific type of [beta]-lactamase, showing specificity for penicillins, again by hydrolysing the beta-lactam ring.
Beta-lactamases are enzymes that cleave the beta-lactam ring, opening up the structure and destroying the ability of the beta-lactam to bind to its target.
Beta-lactam antibiotics--most of which are either penicillins or cephalosporins--have a beta-lactam ring that is essential to their activity, the inhibition of bacterial cell wall synthesis.

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