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beta-lactamase
(redirected from Betalactamase)

   Also found in: Medical, Wikipedia 0.02 sec.
beta-lactamase [¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.


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Using amoxicillin-clavulanate in combination with ceftazidime, cefiriaxone, and aztreonam, we performed the double disk synergy test to determine whether this strain was an extended-spectrum betalactamase producer as described elsewhere (3); augmentation of the zone at the junction of amoxicillin-clavulanate and aztreonam/cefiriaxone/cefiazidime zones confirmed that indeed it was.
 
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