bicuculine

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bicuculine

[bī′kü·kyə‚lēn]
(organic chemistry)
C20H17NO6 A convulsant alkaloid found in plants of the family Fumariaceae.
References in periodicals archive ?
Bicuculline infusions advance the timing of luteinizing hormone surge in proestrous rats: comparisons with naloxone effects.
A] (type A [gamma]-aminobutyric acid) receptor antagonist bicuculline (BIC) triggers dendritic growth via transient rather than prolonged activation of [Ca.
Thirty minutes after the oral administration of KSS, bicuculline ([GABA.
Thirty minutes after the inhalation of KSS, bicuculline (3 mg/kg, i.
Bicuculline did not reverse the prolongation of sleeping time induced by KSS inhalation (Fig.
The effects of strychnine, bicuculline, and ketamine on immersion-inhibited dorsal horn convergent neurons in intact and spinalized rats.
Prenatal exposure to the pesticide dieldrin or the GABA(A) receptor antagonist bicuculline differentially alters expression of GABA(A) receptor subunit mRNAs in fetal rat brainstem.
Pleuvry BJ (1994) The activity of opioid analgesics in seizure models utilizing N-methyl-Das-partic acid, kainic acid, bicuculline and pentylenetetrazole.
Similar to what occurred in the interaction with nantenine, phenytoin heightens the actions of convulsant agents, such as bicuculline and picrotoxin, which possess mechanisms involving the reduction of the inhibitory gabaergic transmission (Stone and Javid, 1982).
Water extract of Leonotis leonurus was tested for anticonvulsant activity against seizures produced in mice by pentylenetetrazole, picrotoxin, bicuculline and N-methyl-DL-aspartic acid (intraperitoneal injections).
leonurus on chemically induced seizures by pentylenetetrazole, picrotoxin, bicuculline and N-methyl D-L-aspartic acid in mice.
Bicuculline (Sigma) and diazepam (Valium[R], Roche, South Africa) were suspended in a minimum amount of Tween 80 and Polyethylene glycol 400 (Flucka AG, Buchs) respectively, and adjusted to an appropriate volume with physiological saline.