binding site

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binding site

[′bīn·diŋ ‚sīt]
(chemistry)
References in periodicals archive ?
The promoter region of the mouse Nanog was found to contain two binding sites, one for Kruppel-like-zinc-finger transcription factor (KLF) and one for Sp1, which are indispensable for activation of the Nanog promoter (Wu and Yao, 2006).
It was found that the experimental data fit well with the Langmuir's binding theory and the system behaved as a system with two classes of binding sites (high-affinity and low-affinity binding site).
The binding sites of E2 were further explored in this paper to clarify the mechanism of E2 in the infection of hepatocytes.
The researchers showed that the number of evolutionary adaptations to the part of the machinery that regulates genes, called transcription factor binding sites, might be roughly equal to adaptations to the genes themselves.
These observations and the fact that biosynthetic processing in the liver hepatocyte requires noncovalent association prior to disulfide bond formation indicates C8[alpha] and C8[gamma] contain mutually recognizable binding sites.
The model predicted specific binding sites for C[O.
If choline is added to a culture of pneumococci, the molecules occupy the choline binding sites of the CBPs so that the proteins no longer can bind to the cell walls of the pneumococci.
Currently, the stoichiometry of iron to frataxin is unknown, as is the exact iron binding sites.
Therefore, when evaluating interactions among drugs, it is important to be aware of possible identities of their binding sites on the protein because any alteration in drug-binding to HSA, including binding of the antihypertensive drugs, could lead to a change in pharmacokinetic properties.
3]H]estradiol binding sites and thus antagonizes estrogenic response through nonclassical pathways (Maggiolini et al.
125]I]D-147 in comparison to known binding sites of other DAT inhibitors.
The C8a subunit contains distinct binding sites for C8b, C8g, C9, and the complement regulatory protein CD59.