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biofilm
(redirected from Biofilms)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
biofilm [′bīยทō‚film]
(microbiology)
A microbial (bacterial, fungal, algal) community, enveloped by the extracellular biopolymer which these microbial cells produce, that adheres to the interface of a liquid and a surface.

Biofilm

An adhesive substance, the glycocalyx, and the bacterial community which it envelops at the interface of a liquid and a surface. When a liquid is in contact with an inert surface, any bacteria within the liquid are attracted to the surface and adhere to it. In this process the bacteria produce the glycocalyx. The bacterial inhabitants within this microenvironment benefit as the biofilm concentrates nutrients from the liquid phase. However, these activities may damage the surface, impair its efficiency, or develop within the biofilm a pathogenic community that may damage the associated environment. Microbial fouling or biofouling are the terms applied to these actual or potentially undesirable consequences.

Microbial fouling affects a large variety of surfaces under various conditions. Microbial biofilms may form wherever bacteria can survive; familiar examples are dental plaque and tooth decay. Dental plaque is an accumulation of bacteria, mainly streptococci, from saliva. The process of tooth decay begins with the bacteria colonizing fissures in and contact points between the teeth. Dietary sucrose is utilized by the bacteria to form extracellular glucans that make up the glycocalyx and assist adhesion to the tooth. Within this microbial biofilm or plaque the metabolic by-products of the bacterial inhabitants are trapped; these include acids that destroy the tooth enamel, dentin, or cementum.



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While we have been taught to consider organism infection to involve freely circulating organisms, what Olmstead refers to as "planktonic growth," it is more likely that organisms congregate in biofilms.
See the Research for Yourself on Plaque Biofilms and Antimicrobial Mouth Rinses According to a special 2007 supplement to the Journal of Dental Hygiene, when considering the oral environment, about 20 percent is occupied by tooth surfaces, that is, those areas targeted for toothbrushing and flossing.
Chunqi Jiang, a research assistant professor in the Ming Hsieh Department of Electrical Engineering-Electrophysics, and Parish Sedghizadeh, assistant professor of clinical dentistry and Director of the USC Center for Biofilms, describe biofilms as complex colonies of bacteria suspended in a slimy matrix that grants them added protection from conventional antibiotics.
 
 
 
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