A year ago, Dr Mark Keating, who studies regeneration in zebra fish (which can re-grow fins, scales, spinal cord and part of its heart), identified a gene essential for initiating blastema
formation when the fish's tail fin is cut.
For some reason, people and other nonurodele vertebrates lack this ability to create a blastema
The researchers found that the fish uses a special genetic trick that allows the acid to control the formation of blastema
, which means the animal is able to produce a store of cells that can rebuild the fin.
Nodular renal blastema
, renal dysplasia and duplicated collecting systems.
30-32) During nephrogenesis, PAX-2 appears very early in the renal blastema
and promotes mesenchymal cell proliferation and apoptosis, and mesenchymal-epithelial transformation, with formation of immature renal tubules and glomeruli.
Unlike mammals, which heal wounds by forming a scar, these mice begin by forming a blastema
, a structure associated with rapid cell growth.
Adult Wilms tumor is a triphasic neoplasm composed of a mixture of blastema
, epithelium, and/or stroma.
Washington, March 27 (ANI): Scientists at the Pentagon have completed the first phase of their plan to regrow soldiers' limbs, by turning human skin into the equivalent of a blastema
- a mass of undifferentiated cells that can develop into new body parts.
The latter postulate followed the delineation by Kupffer, (30) Huber, (22) and Brodel (23) of the dual role of the ampullary bud and renal blastema
in renal nephrogenesis.