Objective: Originally, this blind study was designed to check whether blood smears
constitute reliable tools to determine sex.
Reactive neutrophilias, joint fluid crystal exams, newborn blood smears
, cytopenias on known cancer chemotherapy patients, and negative body fluid smears were excluded.
A repeat blood smear
1 week after starting antimicrobial drug therapy showed no parasites.
Two siblings were diagnosed as CDS based on physical examination, peripheral blood smear
findings, and mutation analysis.
For decades, light microscopy of blood smears
has been the gold standard in the diagnosis of malaria (2).
In this study, we sought to determine the minimum blood concentration of yeast necessary to allow a reliable diagnosis of fungemia by blood smear
review, and to determine factors that may influence the likelihood of a successful diagnosis by this approach.
Therefore, it is speculated that variability in blood smear
features, such as smear thickness, cell spread, and, therefore, surface area, cell touching, uneven spatial cell distribution (depending on areas of the blood smears
), and the similar appearance of thrombocytes and small avian lymphocytes could contribute to the results.
Aggregation of platelets was observed via microscopic examination of the peripheral blood smear
(Figure 1A and 1B).
All reported cases have been diagnosed by identification of spirochetes in blood smears
or by quantitative buffy coat analysis.
0 0 SPR--Slide positivity rate; SFR--Slide falciparum rate; API--Annual parasite rate; ABER--Annual blood smear
Project leader Dr Lisa Ranford-Cartwright said: "The current way of diagnosing is using a blood smear
on a slide and examining it on a microscope.
The bone marrow blasts were similar to those seen in the peripheral blood smear