biopsy

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Related to Bone marrow biopsy: bone marrow transplant, Bone marrow cancer

biopsy

(bīäp`sē), examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. Incisions may be made and total or partial lesions removed in the form of wedges or cylindrical pieces, or scrapings of the surface membranes of internal organs may be collected. Needlelike instruments may be used to pierce the tissues and remove soft inner material. Once the tissue specimen has been obtained it is fixed, i.e., membrane proteins and enzymes are stabilized and chemical and histologic analyses are carried out by pathologists. Tumors are routinely biopsied in order to determine whether they are malignant. Fine needle aspiration is a technique more readily used for certain tumors or lesions because it is less expensive and damaging than traditional surgical biopsy.

biopsy

[′bī‚äp·sē]
(pathology)
The removal and examination of tissues, cells, or fluids from the living body for the purposes of diagnosis.

biopsy

1. examination, esp under a microscope, of tissue from a living body to determine the cause or extent of a disease
2. the sample taken for such an examination
References in periodicals archive ?
Routine bone marrow biopsy has little or no therapeutic consequence for positron emission tomography/computed tomography-staged treatment-naive patients with Hodgkin lymphoma.
When disseminated TB is suspected in immune-competent adults, blood culture offers a safer, less invasive and cheaper investigation than bone marrow biopsy.
A complete blood count, differential, comprehensive metabolic panel, APTT/PTINR, fibrinogen, D-Dimer, and periodic bone marrow biopsy and aspirate are the most common tests performed to evaluate the patient's condition.
This lady also had a significant peripheral eosinophilia unresponsive to anti parasitic chemotherapy, a normal bone marrow biopsy aspirate and p-ANCA, which was non reactive thus ruling out parasitic infestations, collagen diseases such as Churgh-Strauss Syndrome and haematological malignancies.
When findings are negative for this mutation, the patient should undergo analysis for the JAK2 exon 12 mutation, and the minor criteria should be evaluated by means of bone marrow biopsy (5).
Over the next year, though, Vicky's condition started to deteriorate further as her platelet counts continued to fall and in July 2009 another bone marrow biopsy was carried out.
Five years after therapy another bone marrow biopsy was performed which demonstrated similar morphology to the original diagnosis, but cytogenetic analysis demonstrated 3 out of 20 metaphases with a deletion of the long arm of chromosome 20 with no other significant cytogenetic anomaly.
Trephine Bone Marrow Biopsy, Renal Pathology, Molecular Genetics and Virology workshops will also be part of the event.