Boswellic acids (BA), a mixture comprised of four major pentacyclic triterpene acids: beta-boswellic acid, 3-acteyl beta boswellic acid, 11-keto-beta-boswellic acid and 3-acetyl-11-keto-beta-boswellic acid, isolated from the oleo gum resin of Boswellia serrata
is reported to be effective as anti-inflammatory (Singh et al.
Planta Medica, 64, 328 (1998); Boswellia serrata
Is H15 (resin extract of Boswellia serrata
, "incense") a useful supplement to established drug therapy of chronic polyarthritis?
Salviae officinalis Carbon dioxide/isopropyl folium alcohol Boswellia serrata Boswellia serrata
Ethanol (70% v/v) ROXB.
Bone & Joint Ingredients: Chondroitin sulfate, glucosamine HCl, boswellia serrata
, MSM, curcumin 95%
, known as Gajabhakshya in San-skrit, implying its ingestion by elephants has been used in the Ayurvedic medicine since antiquity.
Key words: Boswellic Acid (BA), Boswellia serrata
Extract (BSE), Osteoarthritis of knee (QA knee), Non Steroidal anti-inflammatory Drugs (NSAIDs), Adverse Drug Reactions (ADRs)
Other anti-inflammatory herbs include boswellia serrata
, ashwagandha, nettle, turmeric, cayenne, white willow, cat's claw and devil's claw.
Joint Health Products: Chondroitin granules, glucosamine sulfate and HCL, Kolla II[TM] unhydrolyzed collagen type II, boswellia serrata
, hyaluronic acid
Efficacy and tolerability of Boswellia serrata
extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial.
, an Ayurvedic herb that has been used for thousands of years for arthritis symptoms, is another possible option for PsA, as it has also been shown to inhibit TNF-a and II (35) Additionally, boswellic acids inhibit the synthesis of 5-lipoxygenase (5-LOX) and leukotriene B4 (LTB-4).
The cream of Boswellia serrata
Roxb extract standardized for 5% of 95% 3-O-Acetyl-ll-Keto Beta Boswellic Acid (AKBBA) was studied in an open label, multi-centered phase III clinical trial, evaluating 200 psoriatic patients with application of AKBBA cream three times daily for a period of 12 weeks.