Brush Border

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brush border

[′brəsh ‚bȯr·dər]
(cell and molecular biology)
A superficial protoplasic modification in the form of filiform processes or microvilli; present on certain absorptive cells in the intestinal epithelium and the proximal convolutions of nephrons.

Brush Border


the aggregate of rod-shaped structures on the surface of certain cells in animals and humans. The brush border consists of separate cytoplasmic processes arranged like a brush along the free margin of the cells of the excretory ducts of the salivary glands, the convoluted uriniferous tubules of the kidney, and certain other epithelial cells. By substantially increasing the cell surface, the brush border promotes more intensive absorption and excretion of matter.

References in periodicals archive ?
Urinary trehalase as a specific indication of renal brush border damage.
Brush border membrane sucrase-isomaltase, maltase-glucoamylase and trehalase in mammals.
This cholesterol is absorbed by the brush border site and enters the bloodstream.
In the present study, tubular necrosis, infiltration of lymphocytes in the interstitial spaces with loss of brush border was observed in most kidney sections.
By contrast, amino acid absorption is dependent on a gradient of sodium ions across the brush border membrane of the intestinal epithelial cells.
The NEPHROSCREEN(TM) assay is based on the detection of Adenosine Deaminase Binding Protein (ADBP) in urine, which is released from kidney brush border epithelial cells into the urine during Acute Renal Failure (ARF).
A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes.