carboxyl terminal

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carboxyl terminal

[kär′bäk·səl ′tər·mən·əl]
(biochemistry)
The end of a polypeptide chain with a free carboxyl group.
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References in periodicals archive ?
Since there is a dramatic decrease in efficiency of permeabilization of the membrane by VCC50 relative to the holotoxin, it is possible that truncation of VCC at the C-terminus end abrogates the pore-formation process at the pre-pore assembly stage.
Differences in amino acid sequences between the 5 ER-B isoforms start at amino acid 469 within the ligand binding domain and extend to the C-terminus (4,5) and may have different functions.
A poly-histidine tag is an amino acid motif in proteins that consists of multiple histidine (His) residues, mostly located at the N- or C-terminus of the protein.
By fitting into the C-terminus of the proximal Tpm3.
The antibodies will be directed against the C-terminus of the heavy chain and the light chain of each of these three BoNTs, as these domains contain neutralizing epitopes, according to the latest scientific data.
Furthermore, to reduce the bias of oversampling from any 1 location, we included only viruses with unique nucleotide sequences in the C-terminus region in the analysis.
The functions of this surface-exposed Lpp have not been determined; however, the C-terminus is lysine rich, and other bacterial proteins with C-terminal lysines have been shown to bind plasminogen (2).
USPTO allows claims directed to methods of treating Alzheimer's disease using therapeutic antibodies that recognize the free C-terminus of Beta Amyloid 1-40
Modification of cTnI can also occur through selective proteolysis at the N- and/or C-terminus with increasing myocardial ischemia (5, 9-11) or pressure overload (12).
Their N-terminus consists of a putative functional phytochrome sensory module including PAS (Per / Arnt / Sim), GAF (cGMP specific phosphodiesterase/ adenylate cyclases / formate hydrogen lyase transcription) and PHY (phytochrome) domains, whereas the C-terminus contains a nearly complete phototropin with two LOV (Light, Oxygen and Voltage-sensing) and one STKc (Serine/Threonine protein kinases, catalytic) domains.
GFP (Green Fluorescent Protein) was fused to the c-terminus of M46 from strains WU24 and G186AS.
If the C-terminus carboxylic acid group, (C=O)OH, is replaced with an amide group, (C=O)N[H.