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cyclic AMP-dependent protein kinase
(redirected from CAMP-dependent protein kinase)

   Also found in: Medical, Wikipedia 0.01 sec.
cyclic AMP-dependent protein kinase [¦sī·klik ¦ā¦em¦pē di¦pen·dənt ‚pro‚tēn ′kī‚nās]
(biochemistry)
A serine/threonine protein kinase that phosphorylates a variety of substrates and regulates many important processes such as cell growth and differentiation and the flow of ions across the cell membrane. Also known as protein kinase A; PKA.


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Activation of the GLP-1 receptor results in the stimulation of adenylyl cyclase, leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) and the cAMP-dependent protein kinase A (PKA) activation in the pancreatic tissue [10,11,14,22].
In this study we established cooperative interaction between substrate binding sites of the cAMP-dependent protein kinase catalytic subunit (protein kinase A, EC 2.
But the trio acted synergistically to upregulate a regulatory subunit of cAMP-dependent protein kinase, a ubiquitous protein involved in neurologic pathways and a key regulator of neuronal growth in the clam embryo model.
 
 
 
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