Epidermis-to-dermis migration of immature Langerhans cells upon topical irritant exposure is dependent on CCL2 and CCL5
A botanical extract from channel flow inhibits cell proliferation, induces apoptosis, and suppresses CCL5
in human endometriotic stromal cells.
CCL3, CCL4 and CCL5
produced by Th1 cells favor differentiation of CD4T-cell into Th1-type, activate macrophages in synergism with IFN-[gamma], acting like cytokines of type
An interrogation was conducted using a microarray dataset to evaluate CCR5 and CCL5
expression in the context of 2,254 patient breast cancer samples.
The transcriptional profile of several other chemokines, CXCL1, CXCL5 and CCL5
, was investigated.
Expression of CCL5
(Rantes) and CCR5 in prostate cancer.
It was found that after IL-9 neutralization, mRNA expressions of CCL5
and Vcam-1 were significantly decreased in anti-IL-9 Abs group, compared with IgG group (CCL5
: t = −5.
Vanhove, "Control of transplant tolerance and intragraft regulatory T cell localization by Myeloid-derived suppressor cells and CCL5
," Journal of Immunology, vol.
For example, IL-15 upregulates expression of chemokines like CCL2, CCL5
, and CXCL10 and increases infiltration of mononuclear cells, promoting inflammation in NAFLD .
In the study, the researchers demonstrate that the chemokine CCL5
helps to direct the recruitment of EPCs to sites of wounding by acting on the chemokine receptor CCR5.
In order to better understand the early events on the host-parasite interactions, in this paper, we evaluated the production of proinflammatory (IFN-[gamma], IL-12p70, CCL3, CCL4, CCL5
, CXCL10) and of anti-inflammatory (IL-10, IL-13) cytokines, chemokines and chemokine receptors taking advantage of the in vitro priming system using peripheral blood mononuclear cells (PBMCs) from healthy individuals stimulated by live promastigotes of L.
binds to the CCRX receptor subset) (2).