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CCR5
(redirected from CCR5 receptor)

   Also found in: Medical, Wikipedia 0.01 sec.
CCR5
(medicine)
Belonging to the seven-transmembrane chemokine receptor family, the major cofactor for primary macrophage-tropic human immunodeficiency virus-1 strains.


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ENTRY INHIBITORS MARAVIROC Maraviroc (Pfizer) is the first CCR5 receptor antagonist, licensed for the treatment of HIV infection.
This new class of HIV drugs blocks HIV from attaching onto the CCR5 receptor on the T-cell, making it hard for the virus to enter T cells.
That research suggests that the connection might be through the CCR5 receptor, the major coreceptor of HIV on CD4 cells.
 
 
 
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