CD4


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CD4

(immunology)
A T-cell signaling and/or co-stimulatory monomeric transmembrane glycoprotein involved in major histocompatibility complex II adhesion.
References in periodicals archive ?
Patients also started treatment quicker after point-of-care CD4 testing was introduced.
A study conducted on 232 healthy Asian individuals reported a wide range of CD4 cell counts, (401 to 1451 cells/[micro]l) with a mean and median of 838 and 814 cells/[micro]l respectively (54).
Clinicians rely on accurate CD4 values, despite this variability, to make decisions regarding ART initiation and management.
Expected age at death for men and women with HIV differed according to CD4 count when antiretroviral therapy began.
Association of goat (Capra hircus) CD4 gene exon 6 polymorphisms with ability of sperm internalizing exogenous DNA.
Steven Reid, Project Manager of the CD4 Initiative from the Division of Medicine at Imperial College London.
Whether or not this diagnosis was included in the analysis, however, CD4 counts were related to disease events.
A recent study comparing the cost-effectiveness of CD4 counting to total lymphocyte count testing (TLC) and viral load (VL) testing found that in the absence of second line ARV, CD4 tests are a more cost effective laboratory testing strategy for managing HIV infection.
The analyses included 635 patients who had a baseline CD4 cell count on March 1, 2000, and at least one clinic visit or hospitalization later in the study period; half were followed up for at least seven months.
IRD has been described as occurring in 30% to 40% of those with very low CD4 counts when they begin HAART, developing within the first few months of treatment as the CD4 count rises.
In three of the four volunteers, the number of CD4 T cells harboring HIV dropped by three-fourths.