cyclin-dependent kinase

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cyclin-dependent kinase

[¦sī·klin di¦pen·dənt ′kī‚nās]
(cell and molecular biology)
A family of kinases that, once activated by cyclin, regulate the cell cycle by adding phosphate groups to a variety of protein substrates that control processes in the cycle. Abbreviated Cdk.
References in periodicals archive ?
For example, we know a faulty CDKN2A and CDK4 gene indicates that you're at greater risk for melanoma.
Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclindependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression.
The cdk4 gene is localized to human chromosome segment 12q13-14, which also contains mdm2.