DNA microarray

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Related to CDNA microarray: Oligonucleotide microarray

DNA microarray

[¦dē¦en¦ā ′mī·krō·ə‚rā]
(cell and molecular biology)
A microscopic spot containing identical single-stranded polymeric molecules of deoxyribonucleotides (DNAs), usually oligonucleotides or complementary DNAs, attached to a solid support (such as a membrane, a polymer, or glass) used to simultaneously analyze the expression levels of the corresponding genes.
References in periodicals archive ?
In conclusion, the present study analyzed the differentially expressed genes in urine exfoliated urothelial cells with SSH and cDNA microarray which provided a new and comprehensive expression profile of BTCC.
One important task involved in the analysis of cDNA microarray images is the gridding (addressing) of the spots.
cDNA microarray analysis in multiple sclerosis lesions: detection of genes associated with disease activity.
Eagle's minimum essential medium (MEM) and anti-DNP IgE (monoclonal anti-DNP) were purchased from Sigma; fetal calf serum (FCS) was from Gibco; the cDNA microarray system (CodeLink[TM] Bioarray System) and PCR kit (illustra[TM] Ready-to-Go RT-PCR Beads[TM]) were from GE Healthcare; the total RNA extraction kit (RNeasy[TM] Mini) was from Qiagen; protease inhibitor cocktail (Complete Mini) and phosphatase inhibitor cocktail (phosSTOP) were from Roche; the BCA[TM] Protein Assay Kit was from Pierce; other chemicals were from Wako Pure Chemical Industries.
Finally, Lorin and colleagues (2001) used cDNA microarray analyses to compare affected and unaffected brain tissue obtained after death from six patients with AD and nine control subjects.
Use of a cDNA microarray to analyse gene expression patterns in human cancer.
Using a cDNA microarray containing about 7,000 genes, Seki et al.
Agilent released its Rat cDNA Microarray kit, its fourth cDNA microarray kit.
Topics include a means for comprehensive analysis of the effect of microarray data preprocessing methods on differentially expressed transcript selection, differentiation detection in microarray normalization, spatial de-trending and normalization methods for two-channel DNA and protein microarray data, a survey of cDNA microarray normalization, technical variations in modeling the joint expression of several genes, analysis for certain data normalization, and array-based analysis for the detection of chromosomal aberrations and copy number variations.
ABSTRACT : We created a cDNA microarray representing approximately 3,500 pig genes for functional genomic studies.
Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis.