DNA microarray

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Related to CDNA microarray: Oligonucleotide microarray

DNA microarray

[¦dē¦en¦ā ′mī·krō·ə‚rā]
(cell and molecular biology)
A microscopic spot containing identical single-stranded polymeric molecules of deoxyribonucleotides (DNAs), usually oligonucleotides or complementary DNAs, attached to a solid support (such as a membrane, a polymer, or glass) used to simultaneously analyze the expression levels of the corresponding genes.
References in periodicals archive ?
Use of a cDNA microarray to analyse gene expression patterns in human cancer.
In conclusion, the present study analyzed the differentially expressed genes in urine exfoliated urothelial cells with SSH and cDNA microarray which provided a new and comprehensive expression profile of BTCC.
To get more insight into the mechanism of apigenin action, we performed genome-wide expression profiling of apigenin-treated Huh7 cells using cDNA microarrays (Agilent Whole Human Genome Oligo Microarray) that contain 41,000 genes.
The authors of this proposed method (20) concluded that the new method for gridding, segmentation, and estimation to cDNA microarray images provided better segmentation results in spot shapes as well as intensity estimation than Spot and spot Segmentation R language software.
One important task involved in the analysis of cDNA microarray images is the gridding (addressing) of the spots.
14,18) This study combined the use of cDNA microarray technology and EAE, to identify gene transcripts that are more abundant in either disease states, but not in normal white matter or normal mouse brains.
A COMPARATIVE STUDY OF NORMALIZATION METHODS USED IN STATISTICAL ANALYSIS OF CDNA MICROARRAY DATA
The potentially central role of synaptic vesicle function in the development of AD has been further supported by the findings of Yao and colleagues (2003), who also conducted cDNA microarray analyses of brain tissue from AD patients.
cDNA microarray slide preparation and microarray analysis for the selected SSH cDNA clones was carried out in the Genomics Core Facility, University of Alabama at Birmingham, AL, USA.
Other studies using different techniques including cDNA microarray evaluation of laser microdissected tissue components [19,20], with or without combination with differential display and subtractive cloning procedures [22], proteomics combined with representational difference analysis of cDNAs [70], or SAGE combined with array comparative genomic hybridisation [71], have also recently reported similar findings.
Using a cDNA microarray containing about 7,000 genes, Seki et al.