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Related to CMV retinitis: Acute Retinal Necrosis


Inflammation of the retina.



inflammation of the retina, generally in both eyes. It results from purulent infection of the retinal vessels caused by sepsis, a purulent focus, tuberculosis or other infectious diseases, or poisoning. Retinitis is usually accompanied by inflammation of the choroid (chorioretinitis). A characteristic development is the appearance of scotomata, or areas of depressed vision within the visual field that correspond to the inflammatory focus in the fundus of the eye. If treatment is inadequate, the depression of vision becomes permanent. Treatment depends on the causative disease.

References in periodicals archive ?
CMV retinitis usually occurs in patients with CD4 counts less than 50 cells/[mm.
Food and Drug Administration in March 2001 for the induction and maintenance treatment of CMV retinitis in patients with AIDS, VALCYTE is the leading oral anti-CMV medication with efficacy equivalent to that of the previous gold standard therapy, IV ganciclovir.
The patient population growth is very slow owing to an improvised HIV infection treatment option that brings the incidence of CMV retinitis down.
Kriegsman, CytRx's chief executive officer, said "The key to the UMMS technology for CMV retinitis is the delivery method.
We want viewers to experience the incredible work represented here for its outstanding artistic merit, and then to pause and contemplate the on-going effects of AIDS and CMV retinitis," said Amy Sadao, Executive Director, Visual AIDS.
The researchers recruited a total of 240 AIDS patients right after their CMV retinitis diagnosis.
CMV retinitis can be a life-changing disease that affects 20 to 30 percent of those with HIV/AIDS and can cause blindness if left untreated.
This characterization may lead ophthalmologists to misdiagnose CMV retinitis in patients who seem otherwise healthy.
CMV retinitis is one of the opportunistic infections most closely associated with the early days of the HIV/AIDS epidemic.
The introduction of Valcyte means that patients with acute CMV retinitis will only have to take two Valcyte tablets twice-daily rather than receive two IV infusions a day.
AVAC's vote to recommend approval was made after the company presented data comparing treatment of CMV retinitis with valganciclovir, which is taken orally, to treatment with CYTOVENE(R)-IV (ganciclovir).