The Working Group's Findings demonstrate the need for continued federal involvement as a reinsurer relating to terrorism-related CNBR coverage.
Additionally, the Working Group found some insurance consumers are interested in purchasing CNBR coverage, but for the most part haven't due to limited capacity and relatively high prices.
UnderTRIA, an insurer need not offer any terrorist-related CNBR coverage if it does not offer general CNBR coverage (where permitted by state law).
The GAO report found that insuring CNBR risks is distinctly different from insuring other risks because of the potential for catastrophic losses, a lack of understanding or knowledge about the long-term consequences, and a lack of historical experience with such attacks in the United States.
GAO concluded that, given the challenges faced by insurers in providing coverage for and pricing of CNBR risks, any purely market-driven expansion of coverage is highly unlikely in the foreseeable future.
SDS-PAGE indicated that almost no intact albumin remained after extensive digestion with trypsin (lane 2) or CNBr (lane 3), which should cleave albumin at 6 methionine residues, yielding 3 major fragments from residues 1-123 (A), 124-298 (B), and 299-585 (C) (25).
The total digestion of albumin by CNBr also exhibited little change in assay response vs intact albumin.
Aon's Davis noted there's the additional question of insured versus uninsured losses for CNBR attacks; the market has to be able to price against natural catastrophe losses as well as terrorism losses.
Nutter suggests reinsurers fold CNBR "into a three-layer financing structure" consisting of private industry capacity, new private market financing via a pooling mechanism, and federal participation.
Because the B[beta] chain has a methionine residue conveniently located 9 residues in from the C terminus, we used CNBr digestion to confirm the putative pruning of the terminal glutamine residue.
Tryptic and CNBr peptide mapping located the modification site to the C terminus and yielded a more precise value of 128 Da for the actual decrease in mass.
Five major bands were discernible after CNBr
digestion that corresponded to molecular masses of ~36, 29, 22.