depressant

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depressant,

any one of various substances that diminish functional activity, usually by depressing the nervous systemnervous system,
network of specialized tissue that controls actions and reactions of the body and its adjustment to the environment. Virtually all members of the animal kingdom have at least a rudimentary nervous system.
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. Barbituratesbarbiturate
, any one of a group of drugs that act as depressants on the central nervous system. High doses depress both nerve and muscle activity and inhibit oxygen consumption in the tissues. In low doses barbiturates act as sedatives, i.e.
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, sedativessedative,
any of a variety of drugs that relieve anxiety. Most sedatives act as mild depressants of the nervous system, lessening general nervous activity or reducing the irritability or activity of a specific organ.
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, alcohol, and meprobamatemeprobamate
, tranquilizing drug that acts as a depressant of the central nervous system and is commonly used in the treatment of anxiety and sometimes schizophrenia. Although meprobamate is chemically unlike barbiturates and has lower toxicity, it has similar pharmacological
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 are all depressants. Depressants have various modes of action and effects. Some are primarily used medically to relieve emotion stress, anxiety, and tension; others induce sleep, and still others are used to relieve pain. Depressants also reduce the rate and force of contraction of the heart and are used in the treatment of some forms of heart diseaseheart disease,
any of several abnormalities of the heart and its function in maintaining blood circulation. Heart disease is the cause of approximately half the deaths in the United States each year.
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. Many depressants can induce psychological dependence and addiction (see drug addiction and drug abusedrug addiction and drug abuse,
chronic or habitual use of any chemical substance to alter states of body or mind for other than medically warranted purposes. Traditional definitions of addiction, with their criteria of physical dependence and withdrawal (and often an underlying
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). Typically, overdosage results in confusion, coma, and convulsions. In many cases, the effects of one depressant are intensified if another depressant is taken at the same time, e.g., if barbiturates are taken with alcohol. Because of their potential for abuse, there are now strict regulations regarding the dispensing of many depressant drugs.

depressant

1. Med able to diminish or reduce nervous or functional activity
2. a depressant drug
References in periodicals archive ?
There is an increased risk in patients whose ability to maintain blood pressure has already been compromised by a reduced blood volume or concurrent administration of certain CNS depressant drugs (eg, phenothiazines or general anesthetics).
winterianus leaf essential oil (EO) have a CNS depressant activity and anticonvulsant properties.
Drugs that have CNS depressant effects (eg, alcohol, anxiolytics, barbiturates) may potentiate the CNS effects of zaleplon.
Mixed with opioid painkillers such as Valium and Vicodin, or CNS depressants such as Valium and Xanax, alcohol can slow breathing, causing respiratory failure and death.
The concomitant use of CNS depressants can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death.
Five (38%) reported using ketamine, though this drug has some centrally activating properties, in addition to its CNS depressant activity.
The present data suggest that the elenoside have significant CNS depressant properties in rats.
When considering the use of oxymorphone hydrochloride extended-release tablets in a patient taking a CNS depressant, assess the duration of use of the CNS depressant and the patient's response, including the degree of tolerance that has developed to CNS depression.
The MERN significantly potentiated the duration of phenobarbitone sodium induced sleep in mice suggesting probable tranquilizing action as well as CNS depressant action (Murugesan et al.
GHB is a powerful CNS depressant that appears to work by improving nighttime sleep.
Start with 1/3 to 1/2 the usual dose of OxyContin, monitor patients for signs of sedation and respiratory depression, and consider using a lower dose of the concomitant CNS depressant.