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Furthermore, the antiviral effects were associated with the dose-dependent induction of type I IFNs (IFN-[eth] and IFN-[eth]), ISGs (OAS-1, CXCL10, and ISG15), and cytokine (IL-6) in blood and liver.
Out of 15 pathway annotated genes, 8 muscle-related genes (NRG1, RB1, JUN, CHRNE, CXCL10, IL6, SRF and FGFR2) have a direct relationship in the pathway analysis (Figure 3).
The Penn-led team showed that a specific chemokine, CXCL10, and its receptor were abundantly produced in the brains of T.
2003); up-regulation of the proinflammatory antiangiogenic chemokine CXCL10 (Romagnani et al.
9:15 CXCL4 AND CXCL10 PREDICT RISK OF FATAL CEREBRAL MALARIA,
lari (45), CXCL10 eksikliginde apopitotik notrofillerin ortamdan kaldirilamamasi sonucunda iceriklerinin dokulara yayilarak doku hasarini arttiracaklari ni gostermislerdir.
We also evaluated chemokine genes that have shown altered expression in septic patients: IL8 (interleukin 8), CXCL10 [chemokine (C-X-C motif) ligand 10], PF4 (platelet factor 4), CCL3 [chemokine (C-C motif) ligand 3], and CXCL1 [chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)].
Expression analysis of the T-cell-targeting chemokines CXCL9 and CXCL10 in mice and humans with endothelial infections caused by rickettsiae of the spotted fever group.
Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system.
Thus MDSCs and, in particular, immature macrophages and DCs may participate in the inhibition of CD4+ and CD8+ T cells and the inhibition of their potential anti-angiogenic effect mediated by the type 1 cytokines IFN[gamma], CXCL10 and CXCL9.
In established cutaneous LE lesions, the CXCR3 ligands CXCL9 (interferon-gamma [IFN[gamma]]-induced monokine), CXCL10 (IFN[gamma]-inducible protein 10), and CXCL11 (IFN-inducible T cell alpha chemoattractant) are the most abundantly expressed chemokine family members.
An investigation of the results using human hepatic cell lines in vitro found that recombinant CXCL10 protein inhibits the proliferation of hepatic cells, whereas anti-CXCL10 antibody promotes it.
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