BLC

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BLC

(fluid mechanics)
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The expression of 15 cytokines genes (ADIPOQ, BMP2K, CCL3, CXCL13, IL-16, IL-28B, IL-34, SPP1, TGFB1, TNFAIP2, TNFAIP3, TNFAIP8, TNFAIP8L1, TNFSF11, and TNFSF13B) was significantly upregulated by 2.
The chemokine CXCL13 is a key regulator of B cell recruitment to the cerebrospinal fluid in acute Lyme neuroborreliosis CSF CXCL13 and can be used as a diagnostic marker for infection.
Supporting this view is the finding of increased amounts of CXCL13, which is produced by follicular helper T cells for helping B cells migrate to germinal centers in and around the abnormal cells (5).
The presence of EBV+ B cells, expanded follicular dendritic cell meshworks, and expression of BCL6, CD10, CXCL13, and PD-1 are useful in diagnosing AITL.
Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony stimulating factor.
The qPCR primers and hydrolysis probes for the genes CALM2 [calmodulin 2 (phosphorylase kinase, delta)], CHPT1 (choline phosphotransferase 1), CXCL13 [chemokine (C-X-Cmotif) ligand 13], ERBB2 [v-erbb2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)], ESR1 (estrogen receptor 1), IGKC (immunoglobulin kappa constant), MLPH (melanophilin), MMP1 [matrix metallopeptidase 1 (interstitial collagenase)], OAZ1 (ornithine decarboxylase antizyme 1), PGR (progesterone receptor), RAC-GAP1 (Rac GTPase activating protein 1), RPL37A, TOP2A [topoisomerase (DNA) II alpha 170kDa], and UBE2C (ubiquitin-conjugating enzyme E2C) were identified with Primer Express[TM] software (Applied Biosystems) according to the manufacturer's instructions.
CXCL13 - CXCL13 is a molecule that recruits B cells into inflammatory cell aggregates called follicles.