c-c

(redirected from CXCR1)
Also found in: Medical.

center-to-center, on center

The distance between the center line of one element, member, part, or component (as a stud or joist) and the center line of the next.
References in periodicals archive ?
Autocrine regulation of re-epithelialization after wounding by chemokine receptors CCR1, CCR10, CXCR1, CXCR2, and CXCR3.
Other GPCRs that stimulate invasion with extracellular signal-regulated kinase (ERK) and matrix metalloproteinase 9 (MMP-9) activation include chemokine (C-X-C motif) receptors CXCR1 and CXCR2 (56,57) and CXCR4.
Introduction of additional markers allowed for further characterization of these subsets indicating that CD14lowCD16+ monocytes expressed higher levels of CD43, CD115, CXCL16, CXCR1 and C3AR1 expression whereas CD14highCD16- monocytes exhibited higher levels of CD1d, CD93 and CD114.
La progresion tumoral de este tipo de cancer ha sido asociada a la expresion de ciertas quimiocinas y sus receptores: se encuentra que los tumores mas agresivos presentan niveles altos de CXCR1.
The researchers found that LukED latches onto surface receptors called CXCR1 and CXCR2, creating the same deadly pores that it does when it latches onto CCR5 receptors.
The clinical trial stems from laboratory research at U-M that identified a receptor called CXCR1 on the cancer stem cells that triggers growth of stem cells in response to inflammation and tissue damage.
The biologic role of interIeukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils.
Expression of the chemokine receptors CXCR1 and CXCR2 on granulocytes in human endotoxemia and tuberculosis: involvement of the p38 mitogen-activated protein kinase pathway.
Sin embargo, los neutrofilos RT poseen caracteristicas especiales, verbigracia, los neutrofilos RT tienen una capacidad de adherencia menor, no pueden realizar una nueva transmigracion a traves de la barrera endotelial al tejido inflamado, poseen una vida mas larga (se han recuperado neutrofilos RT luego de 20 horas), realizan mayor produccion de radicales libres ante estimulos menores y tienen mayor rigidez; ademas, sus receptores CXCR1 y CXCR2 estan enormemente disminuidos y por el contrario la expresion de la molecula de adhesion ICAM-1 esta aumentada.
CXCL8 binds to the high-affinity receptors CXCR1 and CXCR2 and evokes neutrophil chemotaxis via activation of the phosphoinositide 3-kinase – phosphatase and tensin homolog pathway.