cadherin

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cadherin

[kad′hir·en]
(cell and molecular biology)
Any of a family of calcium-dependent cell adhesion glycoproteins that play a fundamental role in tissue differentiation and structure.
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Testing for cadherins might be one of those methods.
E-cadherin, one subtype of Cadherins family, is the adhesion molecule found in mammalian cells which is an important factor in cell-cell adhesion.
Epithelial- and neural-type cadherins are members of the cadherin family of glycoprotein adhesion molecules and play an important role in the normal morphogenesis of the developing embryo by sorting cells into specific tissues (12) and by helping in the development and maintenance of the epithelioid phenotype.
Exherin(TM) works by mimicking the N-cadherin active site, thereby preventing cadherins from binding together.
Cadherins are a multifamily of transmembranous, cell-cell adhesion molecules.
One of Adherex's greatest assets is our intellectual property related to cell adhesion molecules, including cadherins, occludin and other adhesion molecules.
Through their interactions with the cytoplasmic catenins,[19] cadherins may be involved in signal-transduction events.
I am intrigued by Adherex' pipeline of compounds targeting cadherins, the proteins that hold tumor blood vessels together.
Cadherins are homotypic adhesion molecules that are important in cell sorting during morphogenesis.
The compounds work by preventing proteins, known as classical cadherins, from properly acting as the "biological glues" that hold tumor cells together.
amp; TORONTO -- Agreement Settles Outstanding Litigation Between the Companies and Further Strengthens Combined Intellectual Property Portfolio Around Cadherins
Profiling the cadherins could potentially be used to aid in the early diagnosis of cancer and to give guidance to doctors on which therapeutic approaches to use at different stages of the disease for each individual patient.