Hofs group has been working on an alternative approach based on calixarenes.
A set of only three calixarenes was sufficient to distinguish histone code elements with a high degree of reproducibility.
Topics include extracting radioactive elements by calixarenes
, the simultaneous removal of radionuclides by extractant mixtures, the radiolysis of solvents used in nuclear fuel reprocessing, automating extraction chromagraphic and ion-exchange separations for radiochemical analysis and monitoring, and neoteric solvents as the basis for alternative approaches to separating actinides and fission products.
Examples include calixarenes
, porphyrins, and macrocyclic polypyridine (17) derivatives.
Topics covered include ligand effects in homogeneous catalysis and rational catalyst design, P-stereogenic ligands, calixarenes
, supramolecular approaches, solid phase synthesis, biological approaches, and solubility and separation.
Specific topics include artificial photochemical devices and machines, rotaxanes as ligands for molecular machines and metal-organic frameworks, strategic anion templation for the assembly of interlocked structures, synthetic nanotubes from calixarenes
, supramolecular architecture based on organometallic half-sandwich complexes, endochemistry of self-assembled hollow spherical cages, polynuclear coordination stages, from structure to function for polyoxometalate nanocapsules, nanocapsules assembled by the hydrophobic effect, opportunities in nanotechnology via organic solid-state reactivity, and organic nanocapsules.
This work is focused on water-soluble organic cage compounds as hosts, including cyclodextrins, cucurbituril, and calixarenes
, resorcinarenes, cavitands, carcerands, and heterocalixarenes
Topics addressed include bioactive macrocyclic peptides and peptide mimics, macrocycles by ring-closure metathesis, supramolecular macrocycle synthesis by H-bonding assembly, cucurbiturils, tetra-urea calixarenes
, shape-persistent macrocycles based on acetylenic scaffolding, supramolecular 3D architectures by metal-directed assembly of synthetic macrocycles, new properties and reactions in self-assembly M6L4 coordination cages, anion-binding macrocycles, and rotaxane and catenane synthesis.
Bridges to applied inorganic chemistry include applications of transition metal complexes of organosulfur compounds as liquid crystals and of inherently chiral calixarenes
as shape-selective molecular sensors.
It was originally published as a tribute to the 50th anniversary of the proposal of a macrocyclic structure for calixarenes (Zinke and Ziegler, Chemische Berichte, Volume 77, p.
A quick search of the literature gave more than 50 papers concerning calixarenes published since these papers were submitted.