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candidiasis

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candidiasis (kăn'dĭdī`əsĭs), infection of the mucous membranes caused by the fungus Candida albicans. Other terms for candidiasis are yeast infection, moniliasis (after a former name of the fungal genus), and thrush thrush, in medicine, infection caused by the fungus Candida albicans, manifested by white, slightly raised patches on the mucous membrane of the tongue, mouth, and throat. The mucous membrane beneath the patches is usually raw and bleeding.
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, the latter term usually being reserved for infection of the mucous membrane of the mouth. The fungus is a normal inhabitant of the mouth and vagina, and its growth is usually kept in check by certain bacteria that also live in these areas. When the balance of these organisms is disturbed by antibiotic treatment, by hormonal imbalances, or by a weakening of the body's resistance to disease (as occurs in AIDS AIDS or acquired immunodeficiency syndrome, fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders.
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), the fungus can begin to proliferate. Candidiasis of the penis (usually traceable to a female with the infection) is called balanitis. Candidal infections are treated with antifungal drugs such as nystatin and miconazole.

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Transnasal esophagoscopy detected florid esophageal candidiasis that involved the entire esophagus down to the gastroesophageal junction (figure).
In analyses of factors associated with bacterial vaginosis, the researchers classified women as either having or not having vaginosis, regardless of whether the women also had vaginal candidiasis; similarly, in analyses of risk factors for candidiasis, a woman's vaginosis status had no bearing on her candidiasis classification.
The four most advanced product candidates include one for the treatment of diaper dermatitis complicated by candidiasis, which is in registration, and three products, which are in or entering Phase 3 clinical trials for the treatment of seborrheic dermatitis, fungal infections, including vaginal candidiasis and onychomycosis, and congenital ichthyosis.
 
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