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carbamazepine
(redirected from Carbamazapine)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
carbamazepine [‚kär·bə′maz·ə‚pēn]
(pharmacology)
C15H12N2O An anticonvulsant that is used in the treatment of epilepsy, and is also useful in the treatment of periods of mania associated with bipolar depression.


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Anticonvulsant hypersensitivity syndrome (AHS) is a rare but potentially life-threatening adverse drug reaction associated with the aromatic anticonvulsant drugs phenytoin, phenobarbital, primidone, and carbamazapine.
Further, the promotional material omitted information regarding the cardiovascular risks of treatment with Covera-HS--use of Covera-HS and beta-blockers may lead to excessive bradycardia and AV block, including complete heart block; combined use with digitalis may lead to digitalis toxicity; and there are potentially serious drug interactions with disopyramide, quinidine, lithium, carbamazapine and theophylline.
With this approval, Zyprexa will become the first medication approved to treat acute manic episodes and prevent recurrence of mania, mixed mania and depression since carbamazapine and lithium became available decades ago.
 
 
 
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